Effect of Penetration Enhancer DMSO on In-Vitro Skin Permeation of Acyclovir Transdermal Microemulsion Formulation.
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چکیده
منابع مشابه
Formulation of microemulsion gel systems for transdermal delivery of celecoxib: In vitro permeation, anti-inflammatory activity and skin irritation tests.
The aim of this study was to develop suitable microemulsion gel systems for transdermal delivery that could assist dissolution enhancement of poorly water soluble celecoxib and thus improve its skin permeability. Long term oral administration of celecoxib causes serious gastrointestinal adverse effects, which makes it a good candidate for transdermal formulations, yet its low water solubility (...
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Transdermal Delivery of Verapamil HCl: Effect of Penetration Agent on In Vitro Penetration through Rat Skin
Article history: Received on: 15/12/2012 Revised on: 24/02/2013 Accepted on: 11/03/2013 Available online: 30/03/2013 Verapamil Hydrochloride is a calcium channel blocking anti-anginal agent. Extensive first pass metabolism, low bioavailability (~20%) and short biological half life (4.8 hrs) altogether makes it an ideal candidate for transdermal drug delivery. The objectives of this study were t...
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ژورنال
عنوان ژورنال: International Journal of Drug Delivery
سال: 2011
ISSN: 0975-0215
DOI: 10.5138/ijdd.2010.0975.0215.03057